MassMine: Collecting and Archiving Big Data for Social Media Humanities Researchers

The MassMine project team representing participants from the Department of English, George A. Smathers Libraries (Libraries), and Research Computing at the University of Florida (UF) requests $60,000 to finish the version 1.0 release, develop a robust training program, and promote the MassMine open source software. MassMine enables researchers to collect their own social media data archives and supports data mining, thus providing free access to big data for academic inquiry. MassMine further supports researchers in creating and defining methods and measures for analyzing cultural and localized trends, and developing humanities research questions and data mining practices. The primary aims of this project are to: 1) refine the MassMine tools to support collection, acquisition, and use of available social media and web data; and, 2) develop a training program and corresponding online resources for supporting the broad use of MassMine by humanities researchers, regardless of experience

The Digital Library of the Caribbean (dLOC): Creating a Shared Research Foundation

This article explains the history and development of the Digital Library of the Caribbean (dLOC) as a research foundation for reading, writing, and researching the Caribbean and thus as part of the scholarly cyberinfrastructure for Caribbean Studies. As a research foundation, dLOC includes technical, social, governmental, and procedural supports including open source tools, executive and scholarly advisory boards for governance, permissions-based rights model to support intellectual property as well as cultural and moral rights, and a core support team. As a research foundation, dLOC supports new forms of research as well as new ways of reading and writing Caribbean Studies

Partnerships in agricultural publications: University of Florida's Marston Science Library and the Florida State Horticultural Society

A partnership forged between the George A. Smathers Libraries at the University of Florida and the Florida State Horticultural Society (FSHS) advances access to current and historical publications of the society and exemplifies an opportunity for agricultural librarians. The Public Knowledge Project's Open Journal System (OJS) was developed by librarians at Simon Fraser and Stanford universities to offer free, web-based publication software that promotes open access to journals and supports editorial workflow and publication needs. Collaborations among libraries and content creators that utilize open source tools like OJS are especially beneficial for agricultural organizations with limited financial and staffing resources. This paper examines the current state of library publishing partnerships with external organizations through analysis of survey data collected by the authors, and shares lessons learned from an example partnership. In this example librarians contributed their expertise in peer-review publishing, intellectual property rights, and institutional repositories to develop a customized online journal site using OJS for FSHS in a manner that reflects the publication workflow of the society. Customized features include branding, peer review, member subscription, full-text indexing, and access to archived issues. Trainings on OJS and digital publication service empower subject-area librarians to serve as points of contact for additional collaborations. Utilizing OJS in partnerships between libraries and content creators enhances the relevancy of the library and subject-area librarians while promoting greater access to agricultural information

Resourcing Scholar-Activism: Collaboration, Transformation, and the Production of Knowledge

In this article we offer a set of resources for scholar-activists to reflect on and guide their practice. We begin by suggesting that research questions should be triangulated to consider not only their scholarly merit but the intellectual and political projects the findings will advance and the research questions of interest to community and social movement collaborators

Library Publishing Curriculum Textbook

In the original, modular curriculum (2018) on which this textbook is based, each unit of the Library Publishing Curriculum contained an instructor’s guide, narrative, a slideshow with talking notes, bibliographies, supplemental material, and activities for use in a physical or virtual classroom for workshops and courses. This textbook version, produced in 2021, adapts the original narrative as the primary content (with very little additional editing) and incorporates the bibliographies, appendices, and images from the slideshow into a linear reading and learning experience for use by librarians or students learning on their own or as part of a classroom learning experience. The LPC hopes others use and extend this CC-BY version into even more learning opportunities to help create a more equitable publishing ecosystem

Large-scale pharmacogenomic study of sulfonylureas and the QT, JT and QRS intervals: CHARGE Pharmacogenomics Working Group

Sulfonylureas, a commonly used class of medication used to treat type 2 diabetes, have been associated with an increased risk of cardiovascular disease. Their effects on QT interval duration and related electrocardiographic phenotypes are potential mechanisms for this adverse effect. In 11 ethnically diverse cohorts that included 71 857 European, African-American and Hispanic/Latino ancestry individuals with repeated measures of medication use and electrocardiogram (ECG) measurements, we conducted a pharmacogenomic genome-wide association study of sulfonylurea use and three ECG phenotypes: QT, JT and QRS intervals. In ancestry-specific meta-analyses, eight novel pharmacogenomic loci met the threshold for genome-wide significance (P<5 × 10−8), and a pharmacokinetic variant in CYP2C9 (rs1057910) that has been associated with sulfonylurea-related treatment effects and other adverse drug reactions in previous studies was replicated. Additional research is needed to replicate the novel findings and to understand their biological basis

A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci.

We conducted a multi-stage, genome-wide association study of bladder cancer with a primary scan of 591,637 SNPs in 3,532 affected individuals (cases) and 5,120 controls of European descent from five studies followed by a replication strategy, which included 8,382 cases and 48,275 controls from 16 studies. In a combined analysis, we identified three new regions associated with bladder cancer on chromosomes 22q13.1, 19q12 and 2q37.1: rs1014971, (P = 8 × 10⁻¹²) maps to a non-genic region of chromosome 22q13.1, rs8102137 (P = 2 × 10⁻¹¹) on 19q12 maps to CCNE1 and rs11892031 (P = 1 × 10⁻⁷) maps to the UGT1A cluster on 2q37.1. We confirmed four previously identified genome-wide associations on chromosomes 3q28, 4p16.3, 8q24.21 and 8q24.3, validated previous candidate associations for the GSTM1 deletion (P = 4 × 10⁻¹¹) and a tag SNP for NAT2 acetylation status (P = 4 × 10⁻¹¹), and found interactions with smoking in both regions. Our findings on common variants associated with bladder cancer risk should provide new insights into the mechanisms of carcinogenesis